In aCRF Designing: An Annotated Case Report Form (aCRF) is a PDF document that maps the study data collected in CRF fields to the corresponding variables in the SDTM datasets.
Why aCRF Is Necessary: A good way to understand the study and database ü From the perspective of reviewers, can know the CRF page source of the variables in SDTM when review SDTM define.xml, also can know how the information in every field of CRF map into SDTM database when review aCRF, then get a whole and clear recognition of the study and database quickly.
Standardization CRF & aCRF :The standard CRF is designed based on CDISC standard, make sure one page in CRF can display one domain or one category of domain information as much as possible. q In a new study, we can refer the standard CRF to design CRF, extract the proper pages, modify and add some specific pages according to requirement.